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DAKTARIN Oral Gel is contraindicated in the following situations: In patients with hypersensitivity to miconazole, another ingredient of the formulation, or other imidazole derivatives.
In infants less than 6 months of age or in those whose swallowing reflex is not yet sufficiently developed.
In patients with liver dysfunction.
Use in combination with the following drugs that are subject to metabolism by CYP3A4: (See Interactions): Substrates known to prolong the QT-interval for example, astemizole, bepridil, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole and terfenadine; Ergot alkaloids; HMG-CoA reductase inhibitors such as simvastatin and lovastatin; Triazolam and oral midazolam.
Use of miconazole oral gel in combination with the following drug that is subject to metabolism by CYP2C9 (see Interactions): Warfarin.
